I tried to keep the comic spoiler free, so I will try to do the same for my comments on it. I imported my Paragon Vanguard - Brenna Shepard - and played Mass Effect 3 like it was going to be taken away from me. My time to beat it was about 38 hours, which included a span of 24 hours where I played nearly continuously and completely lost track of what day it was.
Previous Mass Effect Art:
Many of the pieces from this gallery are available as prints through ghostfire.net
or specifically at the ghostfire market